Elevated free fatty acid levels attenuate hippocampal negative feedback inhibition of HPA axis in rats 游离脂肪酸减弱海马对HPA轴的负反馈调控
Feedback inhibition The inhibition of the activity of an enzyme ( often the first) in a multienzyme reaction sequence by the product of that sequence. 在多酶反应体系中,反应的最终产物抑制最初反应酶的活性(通常是第一个酶)。
The mechanism has been termed cumulative feedback inhibition. 这种机制就叫作累加反馈抑制。
A Preliminary Study on Feedback Inhibition of Extracellular Polysaccharide on Ganoderma lucidum 灵芝真菌发酵胞外多糖反馈抑制的初步研究
These results suggest that the negative feedback regulation on DA biosynthesis mediated by DA autoreceptors might be coupled with the inhibition of cAMP dependent phosphorylation of TH through the inhibition of AC, but not of PKA. 结果表明,DA自身受体介导的负反馈调控的机理是通过抑制依赖cAMP的PKA对TH的磷酸化激活,其作用环节在于抑制AC,而不是对PKA的直接抑制。
The antagonization of glycyrrhetic acid ( GA) to the feedback inhibition on adrenal cortex caused 甘草次酸拮抗外源性皮质激素对肾上腺皮质反馈抑制的机理研究
It is indicated that exogenic cortical hormones have a feedback inhibition ef-fect on the secretory function of H/ P/ A, the inhibitory degree of which is related to the con-ditions of the cerebrovascular diseases. 提示外源性皮质激素反馈性抑制H/P/A分泌机能,其程度与脑血管病病情有关。
Such process not only has feedback and inhibition effects on microbial substitution but also directly influence liquor yield and liquor quality. 该过程不但对微生态群落中的菌种演替具有反馈抑制作用,而且直接影响白酒的产量和质量。
Conclusion Topically applied RA increased EGF-R expression, whether it could be a negative feedback inhibition on the over expression in psoriasis needs further investigation. 结论:外用维甲酸可增强表皮生长因子受体的表达,这种增强是否是对银屑病表皮生长因子过度表达的负反馈抑制需进一步研究。
The light use efficiency was higher in the morning and apparent quantum yield owing the photosynthetic feedback inhibition, contrasting to that in the afternoon. 这主要表现在上午的表观初始量子效率比下午大。光合产物对光合作用的反馈抑制会造成这种量子效率的差异性。
The foregoing data reflected a remove of feedback inhibition of estrogen, and suggested that the estrogen played an important regulation role on gonadotropin secretion in male. The site of action was mainly in the hypothalamus. 上述结果是内源性雌激素反馈抑制作用被解除的反映,说明雌激素对调节男子促性腺激素分泌有重要作用,其作用部位主要是在下丘脑。
Conclusion: The influence of SJAMP on the feedback activity of factor ⅷ was caused by the inhibition of thrombin activity. 结论:SJAMP对因子Ⅷ反馈活化的影响,是由于凝血酶活性受抑制所致。
The process of biodegradation of cellulose is actually simultaneous saccharification and fermentation, and feedback inhibition of reducing sugar on cellulose or hemicelluloses may not heavily occur. 纤维素基质固态发酵中木质纤维素的降解过程实际是同步糖化发酵过程,还原糖不会积累形成对纤维素酶、半纤维素酶的反馈抑制;
Investigation on New Separation Methods of Reducing the Feedback Inhibition of Lactic Acid from Fermentation 对乳酸发酵中反馈抑制消除方法的探讨
Enzyme's inactive and membrane damage caused by active oxygen inhibit cell growth, as a result soluble carbohydrate's consumption decreased and its content increased, the soluble carbohydrate inhibit the photosynthesis through feedback inhibition. MDA的增加表明活性氧增多,活性氧通过使酶失活和膜伤害抑制细胞生长,使细胞内糖利用减少,可溶性糖含量增加,进而反馈性地抑制光合作用。
Such feedback inhibition may have relevance in the local regulation of ocular inflammatory processes. 这种反馈抑制与眼发炎过程中的局部调节有关。
A large number of studies show that CGS expression is regulated by feedback inhibition of substrates. 大量的研究表明CGS的表达受到底物的反馈抑制。
It confirms the hippocampus has negative feedback inhibition to the hypothalamus. 证实了海马对下丘脑的负反馈抑制作用。
CGS in Arabidopsis research showed that 30 amino acids in N-terminal between 99-128 have nothing to do with catalyst, the feedback inhibition significantly decreased after removing it. Overexpression of this N-terminal deletion CGS gene is more conducive to enhanced methionine content in transgenic plants. 对拟南芥CGS的研究表明.其N端99-128位的30个氨基酸与催化作用无关,将其删除后反馈抑制作用明显减弱,过量表达这种N端删除的CGS基因更利于培育蛋氨酸含量提高的转基因植物。
At last the improved speech enhancement algorithm is successful operated on the hardware system. The system can play an inhibitory effect on the acoustic feedback, the basic purpose of rapid inhibition of the Howling and a small injury on the sound quality is achieved. 最后在硬件系统上成功运行了所设计的自动声反馈抑制算法,验证了算法的正确性,对声反馈起到了较好的抑制作用,基本达到了迅速抑制啸叫且对音质损伤较小的目的。
Therefore, regulated by means of genetic engineering, the molecular structure of CGS gene needs to be changed to reduce feedback inhibition of substrate. 因此,在利用基因工程手段进行调控时,需对CGS基因的分子结构进行改造,减少底物反馈抑制作用。